Showing posts with label LDL. Show all posts
Showing posts with label LDL. Show all posts

Saturday, December 13, 2014

The much maligned Ghee that is a "magnet" for fraudsters in India! -Consumer in a blind!

Ghee is the Indianized version of butter oil which is a highly valued by-product of dairy industry. Why this is liked very much in India, despite it being demonized for presence of saturated fats and cholesterol? People love it for its delicate flavor that comes from high heat processing of fresh butter in open pans. Compared to other fats, ghee fetches a premium price to the extent of 100 to 150% and almost all diaries, private as well as cooperative, produce them being sold under various brand names. Ghee is also used in a variety of sweetmeat preparations through out the country. The ingenuity of food fraudsters in adulterating this valued fat product has spawned an entire industry that uses solid fats like Vanaspati in such proportions that cannot be easily detected by the hapless consumer. According to a recent report from the food safety authority sources, more than 50% of market samples of ghee are adulterated as discovered during a market vigilance operation and subsequent laboratory tests of seized samples. If this is true imagine the easy money the fraudsters are making through this devious route! 

Assuming that the figures trotted out by the above report is really true, what are its health implications? Antagonists of ghee consumption basically raise three issues regarding the desirability of taking ghee in our foods. First ghee is supposed to contain cholesterol as it is derived from animal sources. This cannot be refuted though the cholesterol content in ghee, about 250 mg % cannot be considered very high since human body does need about 300 mg of this fat emulsifying aid for digestion of fatty foods in the gastrointestinal tract. Second the saturated fat content, about 62% in ghee makes it eminently eligible for raising a red flag as there is a common impression that all saturated fats are bad for the health. Agreed that saturated fat consumption is not encouraged by nutritionists because of its tendency to raise the Low Density Cholesterol ( LDL) levels in the blood which is bad for the heart but consumption of saturated fat to a limited extent is not dangerous as long as major calories come from plant oils of liquid nature. The third issue is presence of trans fats (TF) in ghee which is being condemned world wide for its ill effects on heart. Why this concern about TF which is present only in small quantities in ghee? 

Of course trans fats are not desirable as a general rule but one has to make a difference between naturally occurring TF and man made TF. Hydrogenated Fats ( HF) made in huge quantities on demand by the food industry to incorporate into various processed products contain very high levels of HF, some times as high as 40% and naturally even a 10 gm portion can contribute about 4 gm of TF to the consumer. Unfortunately almost all baked foods are steeped in HF and intake of TF must be much more than what is considered safe. Health agencies all over the world are hesitant to put a "safe limit" for TF as far as human beings are considered and universally a zero tolerance is advocated. However practical ground reality makes it inevitable for humans to imbibe some TF through various foods consumed. This has necessitated for WHO to put an upper limit of TF ingestion equivalent to 1% of calories derived from the foods we consume every day. In the US there is a guideline which says TF consumption should not be more than 2 gm a day per person. 

Incidentally TF is present from 1 to 4% in human milk and naturally the child also imbibes this. But at such levels TF is not considered unsafe for a growing child. Similarly all animal derived milks contain TF to the extent of 2-5% of its total fat content. As a consequence both butter and ghee will contain TF passed on from the fluid milk during processing. One vital difference between saturated fat and TF is that the former just increases the LDL content in blood without any adverse effect on the HDL level. In contrast TF can cause both an increase in LDL and decrease in HDL, a double whammy! Health conscious consumers must avoid consumption of hydrogenated fats like Vanaspati be it any brand if to be protected against heart disease. But ghee cannot be categorized as a dangerous fat measured by any standards. On the contrary there are many reports highlighting the positive properties of ghee for human beings. As true with any food, moderation is always advised while consuming any fatty foods and ghee is no exception to this golden rule.

Talking about the extent of adulteration of ghee in India, one is left with an impression that a proper study has never been made about different markets in the country based on which any conclusion can be drawn regarding this menacing issue. If FSSAI is to be believed more than 60% of milk marketed by private players in the unorganized sector are adulterated and how harmful such a situation can be to the health of our population can be guessed. Similarly if this logic is extended to ghee market, one cannot doubt that most of the samples must be impure, adulterated with hydrogenated fat. Though no precise data is available, the estimated production of ghee in the country is about a million tons and even adulteration at 10% level can be a rewarding effort for the adultrators!. One comforting thought is that this heinous crime is perpetrated mostly by players in the unorganized sector though catching them is much more difficult than those indulging in this practice from the organized sector. Viewed from another perspective, the adulterated ghee containing Vanaspati can increase the TF ingestion among people with undesirable consequences in the long run. Sooner FSSAI takes preventive action to curb the growth of ghee adulteration "industry", better it will be for the health of the citizens of this country. 

V.H.POTTY
http://vhpotty.blogspot.com/
http://foodtechupdates.blogspot.com

Saturday, June 15, 2013

CARNITINE-THE NEW VILLAIN IN HEART ATTACK

"Heart attack" is a much feared "two words" as millions of people across the world fall prey to this disease with high fatality potential. In spite of tons of literature which claim that the reasons of heart attack, also called Myocardial Infraction (MI), are well known, from time to time serious questions are raised regarding the present state of knowledge about this scourge. Over weight, Obesity, Cholesterol, Saturated fat, Trans fats are all being indicted as the villains for causing MI but the ground reality is that no single factor has yet been proved conclusively that will cause the disease. This does not mean that one can violate the existing dietary guidelines evolved based on lot of scientific data and the theory of probability.
The relation between cholesterol and heart attack is well established as the former creates arterial plaques through stubborn deposits on the walls of the arteries thus narrowing down the effective diameter of the blood vessels near the heart. Logically heart needs to pump the blood with more strain in people having such plaques, determined usually by non-invasive techniques like Angiogram or scanning and such strain on the the heart is supposed to cause seizure of the cardiac muscles causing irreversible damage. World has more or less reconciled to surgical intervention like Angioplasty, heart by pass operation etc to deal with medical problems associated with atherosclerosis. Though preventive measures that include prudent dieting to exclude saturated fat, trans fats, high cholesterol containing food components in the diet and restricting red meat are well known, human weakness for rich foods and low will power to control the food intake invariably lead to atherosclerosis. There is also the genetic factor which can cause health conditions vulnerable to heart disease but still appropriate diets and physical exercise can alleviate the danger to a significant extent.
The eternal debate between carnivores and herbivores regarding the advantages of plant foods centers around the fact that red meat is a rich source of cholesterol and regular consumption of saturated fat rich meat can increase the blood cholesterol levels leading to arterial plaque build up. Though this may be factually correct, there is still some  question as to why cholesterol is not metabolized in the body as it is a biological compound necessary for fat metabolism and is produced in the body. The concept of bad cholesterol and good cholesterol is still an accepted one and the ratio of HDL (high density lipoproteins) to LDL (low density lipoproteins) is widely used to monitor the heart health by many doctors. Even this established concept is under a cloud as a result of newer studies which question this theory. In the midst of these uncertainties, one thing is sure-that by-pass surgery or Angioplasty which opens up the arteries in CVD patients do bring relief from symptoms of Angina Pectoris and extend the life span very significantly.
Latest revelation that high levels of saturated fat or cholesterol in the red meat cannot be entirely blamed for heart disease is going to put some of the present thoughts on CVD under a cloud. According to these studies saturated fat and cholesterol play a very small role in causing heart disease and the blame has to go some where else. It is averred that meat consumption causes the bacteria in the intestine of regular meat eaters to generate a lethal chemical from one of the unique amino acids present in meat called Carnitine which leads to conditions ripe for heart disease. Carnitine is a fuel for some species of microorganisms present exclusively in the intestines of carnivores and in the process they produce a lethal chemical called Trimethylamine N-oxide (TMAO) which causes the heart attack. The studies clearly brought out the connection between red meat, carnitine, bacteria, TMAO and heart attack in no uncertain terms. While vegetarians did not show any TMAO in their blood, carnivores had consistently high levels of this chemical. It is the TMAO which facilitates formation of plaques from cholesterol and in the absence of TMAO cholesterol is likely to be metabolized in the body. 
One of the outcomes of the above studies is the safety of the widely prevalent consumption of some of the products containing Carnitine which athletes and sports persons consume for enhancing their performance. While those not used to meat consumption may be relatively safe from the possibility of TMAO formation due to likely absence of TMAO forming bacteria in their guts, there is a greater chance for meat eaters to generate TMAO in their body which my have deadly consequences. Food safety authorities must frown upon the practice of the industry in marketing products containing carnitine to save precious lives!   
These observations are ground breaking in that it opens up a new avenue to tackle CVD through methods that can eliminate the bacteria which converts Carnitine to TMAO. Unfortunately so far there is no clue as to the identity of these bacteria and any antibiotic therapy can be developed only if scientists get a clue regarding their characteristics and metabolic profile. One of the species of microbes called Acinetobacter spp is reported to have the ability to form TMAO from Carnitine and Lecithin but considerable further studies only can throw more light on this area. Of course there will be many questions that will be raised about the universality of the above observations but this is going to be an area which will receive increasing attention from scientists across the world. Probably the day is not too far when meat eaters can safely eat this food with no guilt or fear of the consequences in the form of arterial diseases.  
Having praised the above studies for the new trail blazing revelations, an unbiased observer cannot help asking a simple question as to why some of the vegetarians shunning meat as well as egg are also prone to CVD though their intestine does not contain TMAO forming bacteria and they do not consume Carnitine rich foods? Beef is the richest source of Carnitine. about 100 mg per 100 gm, though pork meat also contains about one fourth to one fifth of that present in beef. As for vegetarians Milk is a minor source of this amino acid (about 2 mg per 100 ml) though it is consumed in large quantities regularly by most vegetarians. The million dollar question is whether there is another TMAO like substance in plant foods that facilitates plaque build up in them? Very inconvenient question which no body can answer for the time being! 
V.H.POTTY
http://vhpotty.blogspot.com/
http://foodtechupdates.blogspot.com